Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7688428 | 0.79 | LMNA (0.56) | TNKSTNKS2LMNAMEN1KMT2A | |
| SCHEMBL24420477 | 0.78 | ALDH1A1 (0.37) | TNKSTNKS2LMNAMEN1KMT2A | |
| SCHEMBL23240599 | 0.78 | TNKS (0.36) | TNKSTNKS2LMNAMEN1KMT2A | |
| SCHEMBL25823793 | 0.74 | TNKS (0.36) | TNKSTNKS2LMNAMEN1KMT2A | |
| SCHEMBL12193478 | 0.74 | POLB (0.44) | TNKSTNKS2LMNAMEN1KMT2A | |
| SCHEMBL29385770 | 0.74 | POLB (0.44) | TNKSTNKS2LMNAMEN1KMT2A | |
| SCHEMBL28671352 | 0.74 | PDE4A (0.46) | TNKSTNKS2LMNAMEN1KMT2A | |
| SCHEMBL5805556 | 0.71 | CYP1A2 (0.49) | TNKSTNKS2LMNAMEN1KMT2A | |
| SCHEMBL30808256 | 0.70 | TNKS (0.54) | TNKSTNKS2P2RX3ALDH1A1CYP1A2 | |
| SCHEMBL23202176 | 0.70 | LMNA (0.37) | TNKSTNKS2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608462-B | 7-alkyl-9-alkoxy/thiopurine-8-ketone compound, and synthesis method and application thereof in medicines | 华南理工大学 | 2021-11-23 | — | — | CN | disclosed |
| CN-109608462-B | 7-alkyl-9-alkoxy/thiopurine-8-ketone compound, and synthesis method and application thereof in medicines | 华南理工大学 | 2021-11-23 | — | — | CN | disclosed |