Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28656141 | 0.89 | ALDH1A1 (0.39) | EGLN1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28654041 | 0.87 | HDAC1 (0.39) | EGLN1PTGS2HDAC3HDAC4HDAC1 | |
| SCHEMBL28651103 | 0.87 | HDAC3 (0.47) | EGLN1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28654314 | 0.86 | GAA (0.44) | LMNAMAPTKDM4EALDH1A1POLB | |
| SCHEMBL28663991 | 0.83 | LIPG (0.39) | EGLN1HDAC6LMNAMAPTALDH1A1 | |
| SCHEMBL28664287 | 0.82 | CACNA1H (0.39) | — | |
| SCHEMBL28658947 | 0.82 | KCNH2 (0.37) | — | |
| SCHEMBL28676235 | 0.82 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL28670645 | 0.81 | MEN1 (0.37) | — | |
| SCHEMBL28658945 | 0.81 | KCNH2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113692276-A | NURR1 receptor modulators | 加利福尼亚大学董事会 | 2021-11-23 | — | — | CN | disclosed |