Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MAPK8 | P45983 | 9/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28676789 | 0.87 | PTK2 (0.47) | PTK2MAPK8MAPK10 | |
| SCHEMBL28667190 | 0.86 | PTK2 (0.51) | PTK2MAPK8MAPK10KMT2AMEN1 | |
| SCHEMBL28660998 | 0.84 | PTK2 (0.49) | PTK2MAPTRAB9AMAPK8MAPK10 | |
| SCHEMBL28930491 | 0.83 | MAPK8 (0.50) | PTK2MAPTRAB9AMAPK8MAPK10 | |
| SCHEMBL30556623 | 0.82 | MAPK8 (0.49) | PTK2MAPTRAB9AMAPK8MAPK10 | |
| SCHEMBL28665656 | 0.81 | MAPK8 (0.58) | PTK2MAPK8MAPK10 | |
| SCHEMBL29064716 | 0.80 | MAPK8 (0.53) | PTK2RAB9AMAPK8MAPK10NPC1 | |
| SCHEMBL29064712 | 0.80 | MAPK8 (0.52) | PTK2MAPTRAB9AMAPK8MAPK10 | |
| SCHEMBL28664704 | 0.80 | MAPK8 (0.50) | MAPTRAB9AMAPK8MAPK10ALDH1A1 | |
| SCHEMBL30556627 | 0.80 | MAPK8 (0.50) | MAPTRAB9AMAPK8MAPK10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113717148-A | Heteroaromatic amide compound, preparation method and application thereof | 上海医药工业研究院 | 2021-11-30 | — | — | CN | disclosed |