Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.58 |
| ▸ | KDR | P35968 | 5/20 | 0.54 |
| ▸ | MKNK1 | Q9BUB5 | 6/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 6/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28660998 | 0.87 | PTK2 (0.49) | MAPK8CNR1PTK2MAPK10 | |
| SCHEMBL28667190 | 0.87 | PTK2 (0.51) | MAPK8CNR1PTK2MAPK10 | |
| SCHEMBL28660995 | 0.81 | PTK2 (0.54) | MAPK8PTK2MAPK10 | |
| SCHEMBL28676789 | 0.80 | PTK2 (0.47) | MAPK8PTK2MAPK10 | |
| SCHEMBL29064716 | 0.78 | MAPK8 (0.53) | MAPK8CNR1PTK2MAPK10 | |
| SCHEMBL28664704 | 0.77 | MAPK8 (0.50) | MAPK8MAPK10 | |
| SCHEMBL30556627 | 0.77 | MAPK8 (0.50) | MAPK8MAPK10 | |
| SCHEMBL28930491 | 0.76 | MAPK8 (0.50) | MAPK8PTK2MAPK10 | |
| SCHEMBL29064712 | 0.75 | MAPK8 (0.52) | MAPK8PTK2MAPK10 | |
| SCHEMBL30556623 | 0.75 | MAPK8 (0.49) | MAPK8PTK2MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113717148-B | Heteroaromatic amide compound, preparation method and application thereof | 上海医药工业研究院 | 2023-09-05 | — | — | CN | disclosed |
| CN-113717148-A | Heteroaromatic amide compound, preparation method and application thereof | 上海医药工业研究院 | 2021-11-30 | — | — | CN | disclosed |