Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 13/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30556627 | 1.00 | MAPK8 (0.50) | MAPK8NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL28676789 | 0.85 | PTK2 (0.47) | MAPK8MAPK10 | |
| SCHEMBL29064716 | 0.83 | MAPK8 (0.53) | MAPK8NPC1RAB9AMAPK10 | |
| SCHEMBL30556630 | 0.80 | MAPK8 (0.49) | MAPK8NPC1RAB9AMAPK10 | |
| SCHEMBL28660995 | 0.80 | PTK2 (0.54) | MAPK8NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL28681050 | 0.79 | MAPK8 (0.50) | MAPK8NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL28667190 | 0.77 | PTK2 (0.51) | MAPK8MAPK10KMT2A | |
| SCHEMBL28665656 | 0.77 | MAPK8 (0.58) | MAPK8MAPK10 | |
| SCHEMBL28660998 | 0.75 | PTK2 (0.49) | MAPK8NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL28930491 | 0.74 | MAPK8 (0.50) | MAPK8NPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113717148-A | Heteroaromatic amide compound, preparation method and application thereof | 上海医药工业研究院 | 2021-11-30 | — | — | CN | disclosed |