Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | RBBP9 | O75884 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.38 |
| ▸ | ADA | P00813 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109510 | 0.86 | METAP1 (0.46) | METAP1ALDH1A1L3MBTL1CASP3SENP8 | |
| SCHEMBL1091450 | 0.81 | NAMPT (0.52) | METAP1CASP3SENP8SENP7SENP6 | |
| SCHEMBL17201513 | 0.78 | ALDH1A1 (0.55) | METAP1ALDH1A1L3MBTL1CASP3SENP8 | |
| SCHEMBL12862721 | 0.78 | L3MBTL1 (0.45) | METAP1ALDH1A1L3MBTL1HSPA9 | |
| SCHEMBL3749548 | 0.77 | METAP1 (0.43) | METAP1ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL6499017 | 0.76 | L3MBTL1 (0.48) | METAP1ALDH1A1L3MBTL1 | |
| SCHEMBL25753489 | 0.75 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1CASP3SENP8SENP7 | |
| SCHEMBL14720 | 0.74 | METAP1 (0.66) | METAP1ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL19520791 | 0.73 | ALDH1A1 (0.49) | ALDH1A1CASP3SENP8SENP7SENP6 | |
| SCHEMBL148962 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113929680-A | Heterocyclic compounds and their use in the prevention or treatment of bacterial infections | 拜欧蒂姆公司 | 2022-01-14 | — | — | CN | disclosed |
| CN-109906226-B | Heterocyclic compounds and their use in the prevention or treatment of bacterial infections | 拜欧蒂姆公司 | 2021-11-02 | — | — | CN | disclosed |
| CN-102146078-A | Substituted propanamide compounds and preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2011-08-10 | — | — | CN | disclosed |