Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 16/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29032071 | 0.84 | EZH2 (0.43) | EZH2 | |
| SCHEMBL28665990 | 0.84 | EZH2 (0.47) | EZH2 | |
| SCHEMBL28665992 | 0.84 | EZH2 (0.47) | EZH2 | |
| SCHEMBL28675432 | 0.78 | EZH2 (0.44) | EZH2 | |
| SCHEMBL28662670 | 0.77 | EZH2 (0.45) | EZH2 | |
| SCHEMBL28662672 | 0.77 | EZH2 (0.45) | EZH2 | |
| SCHEMBL28670089 | 0.76 | EZH2 (0.43) | EZH2 | |
| SCHEMBL23672116 | 0.76 | GPR119 (0.42) | — | |
| SCHEMBL28930299 | 0.74 | EZH2 (0.37) | EZH2 | |
| SCHEMBL16344544 | 0.68 | EZH2 (0.51) | EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113816950-A | Azaindole derivatives, preparation method and application thereof | 四川海思科制药有限公司 | 2021-12-21 | — | — | CN | disclosed |