SCHEMBL29032071

SCHEMBL29032071

CCc1ccnc2c1c(C(=O)O)c(C)n2C(C)C1CCC(O)CC1

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ EZH2 Q15910 16/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28662673 0.84 EZH2 (0.35) EZH2
SCHEMBL23672116 0.83 GPR119 (0.42) —
SCHEMBL28930299 0.81 EZH2 (0.37) EZH2
SCHEMBL28670089 0.81 EZH2 (0.43) EZH2
SCHEMBL28675432 0.80 EZH2 (0.44) EZH2
SCHEMBL30010680 0.79 EZH2 (0.57) EZH2
SCHEMBL16344544 0.74 EZH2 (0.51) EZH2
SCHEMBL23672207 0.73 EZH2 (0.55) EZH2
SCHEMBL23672208 0.73 EZH2 (0.55) EZH2
SCHEMBL22401116 0.69 EZH2 (0.55) EZH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115197194-A ZESTE enhancer homolog 2 inhibitors and uses thereof 四川海思科制药有限公司 2022-10-18 — — CN disclosed
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