Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.34 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28472270 | 0.78 | PRSS1 (0.49) | PRSS1PRSS2PRSS3ALDH1A1CA2 | |
| SCHEMBL1945087 | 0.76 | EPHX1 (0.54) | ALDH1A1MMP9MMP8MMP13LMNA | |
| SCHEMBL28295013 | 0.75 | ALDH1A1 (0.52) | PRSS1PRSS2PRSS3ALDH1A1CA2 | |
| SCHEMBL1404164 | 0.74 | EPHX1 (0.53) | ALDH1A1MMP9MMP8MMP13LMNA | |
| SCHEMBL21359023 | 0.74 | EPHX1 (0.53) | ALDH1A1MMP9MMP8MMP13LMNA | |
| SCHEMBL7642789 | 0.74 | EPHX1 (0.53) | ALDH1A1MMP9MMP8MMP13LMNA | |
| SCHEMBL4555669 | 0.74 | EPHX1 (0.53) | ALDH1A1MMP9MMP8MMP13LMNA | |
| SCHEMBL18248508 | 0.74 | EPHX1 (0.53) | ALDH1A1MMP9MMP8MMP13LMNA | |
| SCHEMBL8763769 | 0.74 | EPHX1 (0.53) | ALDH1A1MMP9MMP8MMP13LMNA | |
| SCHEMBL528414 | 0.71 | EPHX1 (0.56) | ALDH1A1CA2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113614078-A | Compounds, compositions and methods for treating myopia | 爱瑞制药公司 | 2021-11-05 | — | — | CN | disclosed |