Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL286587 | 0.89 | GABRA1 (0.56) | GABRA1 | |
| SCHEMBL285623 | 0.86 | GABRA5 (0.67) | GABRA1GABRA5 | |
| SCHEMBL286586 | 0.85 | GABRA1 (0.62) | GABRA1GABRA5 | |
| SCHEMBL286449 | 0.84 | GABRA1 (0.48) | GABRA1GABRA5 | |
| SCHEMBL286795 | 0.84 | GABRA1 (0.48) | GABRA1 | |
| SCHEMBL287021 | 0.83 | GABRA1 (0.59) | GABRA1 | |
| SCHEMBL286574 | 0.82 | GABRA1 (0.54) | GABRA1GABRA5 | |
| SCHEMBL286260 | 0.82 | GABRA1 (0.54) | GABRA1GABRA5 | |
| SCHEMBL286683 | 0.82 | GABRA1 (0.54) | GABRA1GABRA5 | |
| SCHEMBL286650 | 0.82 | GABRA1 (0.48) | GABRA1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427458-A1 | ISOXAZOLE-PYRIDAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2012-03-14 | — | — | EP | claimed |
| EP-2427458-A1 | ISOXAZOLE-PYRIDAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2012-03-14 | — | — | EP | disclosed |