SCHEMBL28662928

SCHEMBL28662928

Oc1cc2ccccc2cc1Nc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.59
GFER P55789 1/20 0.59
NGLY1 Q96IV0 1/20 0.59
ALDH1A1 P00352 5/20 0.50
HSD17B10 Q99714 4/20 0.50
CYP3A4 P08684 3/20 0.50
HPGD P15428 2/20 0.50
TSHR P16473 3/20 0.48
ALOX15 P16050 2/20 0.48
TP53 P04637 1/20 0.48
CDC25B P30305 1/20 0.48
ATM Q13315 1/20 0.48
HSP90AA1 P07900 1/20 0.45
KDM4E B2RXH2 4/20 0.45
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
TDP1 Q9NUW8 2/20 0.43
GAA P10253 2/20 0.43
GLA P06280 1/20 0.43
RECQL P46063 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25189708 0.85 CXCR2 (0.45) MAPTGFERNGLY1ALDH1A1HSD17B10
SCHEMBL3766360 0.84 MAPT (0.64) MAPTGFERNGLY1ALDH1A1HSD17B10
SCHEMBL10606167 0.81 MAPT (0.41) MAPTGFERNGLY1MEN1KMT2A
SCHEMBL27561763 0.77 CDC25B (0.52) MAPTGFERNGLY1ALDH1A1HSD17B10
SCHEMBL10748929 0.76 TSHR (0.47) ALDH1A1TSHRCDC25BATMKDM4E
SCHEMBL12919804 0.76 PTPN1 (0.50) MAPTGFERNGLY1TSHRTP53
SCHEMBL29773126 0.75 TSHR (0.55) MAPTGFERNGLY1ALDH1A1HSD17B10
SCHEMBL8537743 0.75 MAPT (0.58) MAPTGFERNGLY1ALDH1A1HSD17B10
SCHEMBL10011040 0.75 CYP3A4 (0.55) MAPTALDH1A1HSD17B10CYP3A4HPGD
SCHEMBL10493707 0.75 CAMK2A (0.45) ALDH1A1CYP3A4TSHRKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113474156-B Polyamic acid resin composition, polyimide resin film and method for producing same, laminate, and electronic device and method for producing same 东丽株式会社 2022-04-29 CN disclosed
CN-113474156-A Polyamic acid resin composition, polyimide resin film and method for producing same, laminate, and electronic device and method for producing same 东丽株式会社 2021-10-01 CN disclosed