SCHEMBL3766360

SCHEMBL3766360

c1ccc(Nc2cc3ccccc3cc2Nc2ccccc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.64
GFER P55789 2/20 0.64
NGLY1 Q96IV0 1/20 0.64
ALDH1A1 P00352 7/20 0.60
HPGD P15428 5/20 0.60
HSD17B10 Q99714 4/20 0.60
CYP3A4 P08684 4/20 0.60
ALOX15 P16050 3/20 0.58
TSHR P16473 3/20 0.58
TP53 P04637 1/20 0.58
CDC25B P30305 1/20 0.58
ATM Q13315 1/20 0.58
TDP1 Q9NUW8 6/20 0.52
MAPK1 P28482 2/20 0.52
ALOX12 P18054 1/20 0.52
PTGS1 P23219 1/20 0.52
SLC6A2 P23975 1/20 0.52
PTGS2 P35354 1/20 0.52
HTR2B P41595 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5080930 0.86 HSD17B10 (0.65) MAPTGFERNGLY1ALDH1A1HPGD
SCHEMBL28662928 0.84 MAPT (0.59) MAPTGFERNGLY1ALDH1A1HPGD
SCHEMBL8537743 0.84 MAPT (0.58) MAPTGFERNGLY1ALDH1A1HPGD
Anthracene SCHEMBL27694615 0.83 ALDH1A1 (0.73) MAPTGFERNGLY1ALDH1A1HPGD
SCHEMBL6536800 0.83 ALDH1A1 (0.63) MAPTGFERNGLY1ALDH1A1HPGD
SCHEMBL30777274 0.83 MAPT (0.53) MAPTGFERNGLY1ALDH1A1HPGD
SCHEMBL18271452 0.83 MAPT (0.53) MAPTGFERNGLY1ALDH1A1HPGD
Benz(B)Anthracene SCHEMBL28034891 0.81 ALDH1A1 (0.70) MAPTGFERNGLY1ALDH1A1HPGD
SCHEMBL1901021 0.80 MAPT (0.59) MAPTGFERNGLY1ALDH1A1HPGD
SCHEMBL28146064 0.80 ALDH1A1 (0.80) MAPTGFERNGLY1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3805338-B1 TRANSITION METAL COMPLEXES COMPRISING CARBENE LIGANDS AS EMITTERS FOR ORGANIC LIGHT-EMITTING DIODES (OLEDS) UDC IRELAND LTD (IE) 2024-06-19 EP disclosed
US-20230108701-A1 TRANSITION METAL COMPLEXES COMPRISING CARBENE LIGANDS SERVING AS EMITTERS FOR ORGANIC LIGHT-EMITTING DIODES (OLED'S) UDC IRELAND LTD (IE) 2023-04-06 US disclosed
US-11539005-B2 Transition metal complexes comprising carbene ligands serving as emitters for organic light-emitting diodes (OLED's) UDC IRELAND LIMITED (IE) 2022-12-27 US disclosed
US-11539005-B2 Transition metal complexes comprising carbene ligands serving as emitters for organic light-emitting diodes (OLED's) UDC IRELAND LIMITED (IE) 2022-12-27 US disclosed
EP-3805338-A1 TRANSITION METAL COMPLEXES COMPRISING CARBENE LIGANDS AS EMITTERS FOR ORGANIC LIGHT-EMITTING DIODES (OLEDS) UDC Ireland Limited (IE) 2021-04-14 EP disclosed
EP-3299437-B1 TRANSITION METAL COMPLEXES COMPRISING CARBENE LIGANDS AS EMITTER FOR ORGANIC LIGHT-EMITTING DIODES (OLEDS) UDC IRELAND LTD (IE) 2020-09-23 EP disclosed
US-10784448-B2 Electroluminescent imidazo-quinoxaline carbene metal complexes UDC IRELAND LIMITED (IE) 2020-09-22 US disclosed
US-10784448-B2 Electroluminescent imidazo-quinoxaline carbene metal complexes UDC IRELAND LIMITED (IE) 2020-09-22 US disclosed
US-20200266366-A1 TRANSITION METAL COMPLEXES COMPRISING CARBENE LIGANDS SERVING AS EMITTERS FOR ORGANIC LIGHT-EMITTING DIODES (OLED'S) UDC IRELAND LTD (IE) 2020-08-20 US disclosed
US-20200266366-A1 TRANSITION METAL COMPLEXES COMPRISING CARBENE LIGANDS SERVING AS EMITTERS FOR ORGANIC LIGHT-EMITTING DIODES (OLED'S) UDC IRELAND LTD (IE) 2020-08-20 US disclosed
US-20110049500-A1 TRANSITION METAL COMPLEXES COMPRISING CARBENE LIGANDS SERVING AS EMITTERS FOR ORGANIC LIGHT-EMITTING DIODES (OLED'S) BASF AKTIENGESELLSCHAFT (DE) 2011-03-03 US disclosed
US-20110049501-A1 TRANSITION METAL COMPLEXES COMPRISING CARBENE LIGANDS SERVING AS EMITTERS FOR ORGANIC LIGHT-EMITTING DIODES (OLED'S) BASF AKTIENGESELLSCHAFT (DE) 2011-03-03 US disclosed
US-20110049501-A1 TRANSITION METAL COMPLEXES COMPRISING CARBENE LIGANDS SERVING AS EMITTERS FOR ORGANIC LIGHT-EMITTING DIODES (OLED'S) BASF AKTIENGESELLSCHAFT (DE) 2011-03-03 US disclosed
US-20110049499-A1 TRANSITION METAL COMPLEXES COMPRISING CARBENE LIGANDS SERVING AS EMITTERS FOR ORGANIC LIGHT-EMITTING DIODES (OLED'S) BASF AKTIENGESELLSCHAFT (DE) 2011-03-03 US disclosed
US-20110049499-A1 TRANSITION METAL COMPLEXES COMPRISING CARBENE LIGANDS SERVING AS EMITTERS FOR ORGANIC LIGHT-EMITTING DIODES (OLED'S) BASF AKTIENGESELLSCHAFT (DE) 2011-03-03 US disclosed
US-20110049500-A1 TRANSITION METAL COMPLEXES COMPRISING CARBENE LIGANDS SERVING AS EMITTERS FOR ORGANIC LIGHT-EMITTING DIODES (OLED'S) BASF AKTIENGESELLSCHAFT (DE) 2011-03-03 US disclosed
US-7846763-B2 starting from N,N-diphenylethane-1,2-diamine; bisamine is reacted with triethyl formate in the presence of ammonium tetrafluoroborate; suitable for producing electroluminescence in the blue, red and green regions of the electromagnetic spectrum BASF AKTIENGESELLSCHAFT (DE) 2010-12-07 US disclosed
US-7846763-B2 starting from N,N-diphenylethane-1,2-diamine; bisamine is reacted with triethyl formate in the presence of ammonium tetrafluoroborate; suitable for producing electroluminescence in the blue, red and green regions of the electromagnetic spectrum BASF AKTIENGESELLSCHAFT (DE) 2010-12-07 US disclosed
US-7846763-B2 starting from N,N-diphenylethane-1,2-diamine; bisamine is reacted with triethyl formate in the presence of ammonium tetrafluoroborate; suitable for producing electroluminescence in the blue, red and green regions of the electromagnetic spectrum BASF AKTIENGESELLSCHAFT (DE) 2010-12-07 US disclosed
US-20060258043-A1 Transition metal complexes comprising carbene ligands serving as emitters for organic light-emitting diodes (oled's) BASF AKTIENGESELLSCHAFT (DE) 2006-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110049500-A1 TRANSITION METAL COMPLEXES COMPRISING CARBENE LIGANDS SERVING AS EMITTERS FOR ORGANIC LIGHT-EMITTING DIODES (OLED'S) CHRM1, OCIAD1, OPRD1 MAPT 1981/4885GFER 3045/4885NGLY1 1987/4885
US-20200266366-A1 TRANSITION METAL COMPLEXES COMPRISING CARBENE LIGANDS SERVING AS EMITTERS FOR ORGANIC LIGHT-EMITTING DIODES (OLED'S) CHRM1, OPRD1, DRD1 MAPT 1532/4885GFER 2183/4885NGLY1 2689/4885
US-20110049501-A1 TRANSITION METAL COMPLEXES COMPRISING CARBENE LIGANDS SERVING AS EMITTERS FOR ORGANIC LIGHT-EMITTING DIODES (OLED'S) CHRM1, OCIAD1, OPRD1 MAPT 1981/4885GFER 3045/4885NGLY1 1987/4885
US-10784448-B2 Electroluminescent imidazo-quinoxaline carbene metal complexes OCIAD1, OCIAD2, OXER1 MAPT 603/4885GFER 1217/4885NGLY1 4763/4885
US-11539005-B2 Transition metal complexes comprising carbene ligands serving as emitters for organic light-emitting diodes (OLED's) CHRM1, OPRD1, DRD1 MAPT 1532/4885GFER 2183/4885NGLY1 2689/4885
US-20230108701-A1 TRANSITION METAL COMPLEXES COMPRISING CARBENE LIGANDS SERVING AS EMITTERS FOR ORGANIC LIGHT-EMITTING DIODES (OLED'S) OPRD1, CHRM1, OCIAD1 MAPT 1481/4885GFER 3194/4885NGLY1 2526/4885
US-20110049499-A1 TRANSITION METAL COMPLEXES COMPRISING CARBENE LIGANDS SERVING AS EMITTERS FOR ORGANIC LIGHT-EMITTING DIODES (OLED'S) CHRM1, OCIAD1, OPRD1 MAPT 1981/4885GFER 3045/4885NGLY1 1987/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.