SCHEMBL28662974

SCHEMBL28662974

CO/C=C/c1ccc(OC)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.64
CYP3A4 P08684 2/20 0.64
LMNA P02545 2/20 0.64
ALDH1A1 P00352 2/20 0.64
TP53 P04637 1/20 0.64
TSHR P16473 1/20 0.64
RELA Q04206 2/20 0.61
TRPA1 O75762 1/20 0.61
CYP1A2 P05177 3/20 0.59
CYP1A1 P04798 3/20 0.59
CYP1B1 Q16678 3/20 0.59
ESR1 P03372 2/20 0.59
PTGS2 P35354 2/20 0.59
TUBB4A P04350 2/20 0.59
TUBB P07437 2/20 0.59
TUBA3C P0DPH7 2/20 0.59
AHR P35869 2/20 0.59
TUBA1B P68363 2/20 0.59
TUBA4A P68366 2/20 0.59
TUBB4B P68371 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7868088 1.00 KDM4E (0.64) KDM4ECYP3A4LMNAALDH1A1TP53
SCHEMBL756486 0.86 KDM4E (0.64) KDM4ECYP3A4LMNAALDH1A1TP53
SCHEMBL8741689 0.86 KDM4E (0.46) KDM4ECYP3A4LMNAALDH1A1TP53
SCHEMBL6540540 0.85 PKM (0.66) KDM4ECYP3A4LMNAALDH1A1TP53
SCHEMBL6540537 0.85 PKM (0.66) KDM4ECYP3A4LMNAALDH1A1TP53
SCHEMBL631998 0.85 RELA (0.81) KDM4ECYP3A4LMNAALDH1A1TP53
SCHEMBL699458 0.85 RELA (0.81) KDM4ECYP3A4LMNAALDH1A1TP53
SCHEMBL13790336 0.85 RELA (0.81) KDM4ECYP3A4LMNAALDH1A1TP53
SCHEMBL4881152 0.85 RELA (0.81) KDM4ECYP3A4LMNAALDH1A1TP53
SCHEMBL14950253 0.85 RELA (0.81) KDM4ECYP3A4LMNAALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113683491-A Preparation method of 4- (2-bromoethyl) phenol 王传良 2021-11-23 CN disclosed