Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 14/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28423387 | 0.81 | RPS6KA5 (0.41) | PTK2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL29022362 | 0.81 | PTK2 (0.51) | PTK2KDM4EALDH1A1GAAPOLB | |
| SCHEMBL5608903 | 0.80 | PTK2 (0.54) | PTK2KDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL17622245 | 0.78 | KDM4E (0.54) | PTK2KDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28460368 | 0.74 | POLB (0.46) | PTK2ALDH1A1SMN1; SMN2CYP17A1CYP1A2 | |
| SCHEMBL5662790 | 0.74 | NOTUM (0.41) | KDM4EALDH1A1GAASMN1; SMN2CYP1A2 | |
| SCHEMBL524138 | 0.74 | CDC7 (0.60) | PTK2ALDH1A1POLBMAPT | |
| SCHEMBL31107087 | 0.74 | CDC7 (0.60) | PTK2ALDH1A1POLBMAPT | |
| SCHEMBL19359532 | 0.74 | SMN1; SMN2 (0.47) | PTK2KDM4EALDH1A1SMN1; SMN2CYP17A1 | |
| SCHEMBL29388549 | 0.74 | CDC7 (0.60) | PTK2ALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110252351-B | Application of copper catalyst in catalyzing reaction of 1-pyridyl indole compound and tert-butyl nitrite | 苏州大学 | 2021-12-10 | — | — | CN | claimed |
| CN-110252351-B | Application of copper catalyst in catalyzing reaction of 1-pyridyl indole compound and tert-butyl nitrite | 苏州大学 | 2021-12-10 | — | — | CN | disclosed |