SCHEMBL17622245

SCHEMBL17622245

Cc1cccc2ccn(-c3cccc4c3C(=O)N(c3ccccn3)C4=O)c12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.54
ALDH1A1 P00352 2/20 0.54
GAA P10253 1/20 0.54
MEN1 O00255 4/20 0.45
KMT2A Q03164 4/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
CASP1 P29466 2/20 0.44
MAPT P10636 1/20 0.44
TSHR P16473 1/20 0.44
HTT P42858 1/20 0.44
HBB P68871 1/20 0.44
HPGD P15428 2/20 0.43
LMNA P02545 2/20 0.43
GRM4 Q14833 3/20 0.42
NPC1 O15118 1/20 0.40
S1PR4 O95977 1/20 0.40
POLB P06746 1/20 0.40
XBP1 P17861 1/20 0.40
S1PR1 P21453 1/20 0.40
CCR6 P51684 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11068195 0.82 KDM4E (0.60) KDM4EALDH1A1GAAMEN1KMT2A
SCHEMBL28663530 0.78 PTK2 (0.51) KDM4EALDH1A1GAASMN1; SMN2MAPT
SCHEMBL18263916 0.73 GRM4 (0.55) MEN1KMT2ALMNAGRM4TYMS
SCHEMBL30817653 0.68 ALDH1A1 (0.73) KDM4EALDH1A1GAAMEN1KMT2A
SCHEMBL30817652 0.68 ALDH1A1 (0.73) KDM4EALDH1A1GAAMEN1KMT2A
SCHEMBL7479419 0.68 ALDH1A1 (0.73) KDM4EALDH1A1GAAMEN1KMT2A
SCHEMBL28818121 0.68 DPP4 (0.55) GRM4TYMSGRM1DPP4
SCHEMBL28423387 0.68 RPS6KA5 (0.41) KDM4EALDH1A1GAAMEN1KMT2A
SCHEMBL14357435 0.66 KDM4E (0.74) KDM4EALDH1A1GAAMEN1KMT2A
SCHEMBL8606872 0.66 ALDH1A1 (0.56) KDM4EALDH1A1GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10651394-B2 Organic molecules for use as emitters CYNORA GMBH (DE) 2020-05-12 US disclosed
EP-3246373-B1 ORGANIC MOLECULES FOR USE AS EMITTERS CYNORA GMBH (DE) 2019-01-30 EP disclosed
EP-3137574-B1 ORGANIC MOLECULES FOR USE AS EMITTERS CYNORA GMBH (DE) 2018-04-04 EP disclosed
EP-3246373-A1 ORGANIC MOLECULES FOR USE AS EMITTERS cynora GmbH (DE) 2017-11-22 EP disclosed
US-20170288149-A1 ORGANIC MOLECULES FOR USE AS EMITTERS CYNORA GMBH (DE) 2017-10-05 US disclosed
US-20170288149-A1 ORGANIC MOLECULES FOR USE AS EMITTERS CYNORA GMBH (DE) 2017-10-05 US disclosed
WO-2016042070-A1 ORGANIC MOLECULES FOR USE AS EMITTERS CYNORA GMBH (DE) 2016-03-24 WO disclosed