Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 9/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28663530 | 0.80 | PTK2 (0.51) | PTK2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL29022362 | 0.77 | PTK2 (0.51) | PTK2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL1762583 | 0.75 | PTK2 (0.53) | PTK2MAPT | |
| SCHEMBL29388549 | 0.71 | CDC7 (0.60) | PTK2ALDH1A1MAPT | |
| SCHEMBL31107087 | 0.71 | CDC7 (0.60) | PTK2ALDH1A1MAPT | |
| SCHEMBL524138 | 0.71 | CDC7 (0.60) | PTK2ALDH1A1MAPT | |
| SCHEMBL12528733 | 0.71 | PTK2 (1.00) | PTK2 | |
| SCHEMBL5609346 | 0.70 | MAPT (0.41) | MAPT | |
| SCHEMBL30159009 | 0.69 | CDC7 (0.61) | PTK2 | |
| SCHEMBL28557365 | 0.69 | GAA (0.51) | PTK2KDM4EALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1354887-B1 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INST TECHNOLOGY (US) | 2007-04-25 | — | — | EP | disclosed |
| EP-1097158-B1 | LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES | MASSACHUSETTS INST TECHNOLOGY (US) | 2006-01-25 | — | — | EP | disclosed |
| EP-1354887-A1 | Ligands for metals and improved metal-catalyzed processes based thereon | Massachusetts Insitute of Technology (US) | 2003-10-22 | — | — | EP | disclosed |