SCHEMBL2866385

SCHEMBL2866385

Cc1ccc(C(=O)OC(C)C)c(N)c1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 6/20 0.47
CA1 P00915 6/20 0.47
CA2 P00918 6/20 0.47
CA7 P43166 6/20 0.47
CA9 Q16790 6/20 0.47
CA14 Q9ULX7 6/20 0.47
MAPT P10636 2/20 0.42
POLB P06746 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ALDH1A1 P00352 6/20 0.41
HPGD P15428 2/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 2/20 0.40
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
HSD17B10 Q99714 2/20 0.40
NPC1 O15118 1/20 0.40
CYP4F2 P78329 1/20 0.39
CYP4A11 Q02928 1/20 0.39
KDM4E B2RXH2 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2532174 0.82 ALDH1A1 (0.37) CA12CA1CA2CA7CA9
SCHEMBL1355241 0.80 KDM4E (0.49) CA12CA1CA2CA7CA9
SCHEMBL8763786 0.79 NPC1 (0.50) CA12CA1CA2CA7CA9
SCHEMBL9890969 0.77 POLB (0.38) MAPTPOLBALDH1A1HPGDCYP2C9
SCHEMBL23273084 0.77 ALDH1A1 (0.42) CA12CA1CA2CA7CA9
SCHEMBL272159 0.77 ALDH1A1 (0.54) CA12CA1CA2CA7CA9
SCHEMBL16227696 0.77 CYP2D6 (0.46) CA12CA1CA2CA7CA9
SCHEMBL27661346 0.77 CA12 (0.49) CA12CA1CA2CA7CA9
SCHEMBL29026677 0.77 CA12 (0.45) CA12CA1CA2CA7CA9
SCHEMBL2177470 0.76 HSD17B10 (0.43) ALDH1A1LMNACYP2C9CYP2C19HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100046078-A1 FILTER FOR DISPLAY, PRODUCTION METHOD THEREOF, AND PRODUCTION METHOD OF DISPLAY TORAY INDUSTRIES, INC. (JP) 2010-02-25 US disclosed
EP-2061019-A1 DISPLAY FILTER AND ITS MANUFACTURING METHOD, AND DISPLAY MANUFACTURING METHOD Toray Industries, Inc. (JP) 2009-05-20 EP disclosed