Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | GPX4 | P36969 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13176215 | 0.80 | POLB (1.00) | POLBKMT2ARECQL | |
| SCHEMBL19909698 | 0.77 | CYP1A2 (0.50) | POLBGPX4 | |
| SCHEMBL31395022 | 0.77 | CYP1A2 (0.50) | GPX4KMT2ABTKMEN1 | |
| SCHEMBL32667371 | 0.76 | — | — | |
| SCHEMBL17033931 | 0.76 | GPX4 (0.45) | GPX4KMT2ABTKMEN1 | |
| SCHEMBL19890770 | 0.74 | ALDH1A1 (0.44) | GPX4KMT2AMEN1 | |
| SCHEMBL16075262 | 0.72 | GPX4 (0.54) | GPX4 | |
| SCHEMBL19128259 | 0.72 | POLB (0.80) | POLBKMT2ARECQL | |
| SCHEMBL1447149 | 0.72 | POLB (0.80) | POLBKMT2AMEN1 | |
| SCHEMBL12045719 | 0.72 | POLB (0.80) | POLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113498342-A | Compounds involved in synergistic binding and uses thereof | 锐新医药公司 | 2021-10-12 | — | — | CN | claimed |
| CN-113498342-A | Compounds involved in synergistic binding and uses thereof | 锐新医药公司 | 2021-10-12 | — | — | CN | disclosed |