Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.37 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.34 |
| ▸ | KDM4A | O75164 | 2/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27806009 | 0.86 | KDM4C (0.34) | ENPEPGSTK1LMNASLC22A6KDM4A | |
| SCHEMBL28274858 | 0.84 | FFAR4 (0.49) | TSHRMEN1KMT2ASLC22A6 | |
| SCHEMBL28302777 | 0.82 | FOLH1 (0.42) | NFKB1TSHRCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL28015527 | 0.81 | FFAR4 (0.57) | TSHRBLMMEN1CYP2C19KMT2A | |
| SCHEMBL28826557 | 0.81 | CYP2D6 (0.38) | NFKB1TSHRCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL28648697 | 0.80 | — | — | |
| SCHEMBL7705158 | 0.78 | TSHR (0.52) | NFKB1TSHRCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL28259313 | 0.78 | PLA2G10 (0.38) | NFKB1TSHRENPEPGSTK1LMNA | |
| SCHEMBL8535890 | 0.77 | NFKB1 (0.47) | NFKB1TSHRCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL12498852 | 0.75 | LMNA (0.43) | NFKB1TSHRCYP2D6SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563180-A | (E) Preparation method of (E) -4-ene-1, 8-octanedioic acid | 广东嘉博制药有限公司 | 2021-10-29 | — | — | CN | disclosed |
| CN-113563180-A | (E) Preparation method of (E) -4-ene-1, 8-octanedioic acid | 广东嘉博制药有限公司 | 2021-10-29 | — | — | CN | disclosed |