Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | SDHB | P21912 | 1/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.38 |
| ▸ | SCN4A | P35499 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6714723 | 0.84 | CA12 (0.52) | ASIC3LARS1CA12CA1CA2 | |
| SCHEMBL28663102 | 0.83 | SLC7A5 (0.43) | SLC7A5ABCG2ABCB1CA12CA1 | |
| SCHEMBL725997 | 0.82 | SLC7A5 (0.43) | SLC7A5ABCG2ABCB1CA12CA1 | |
| SCHEMBL31049680 | 0.82 | SLC7A5 (0.43) | SLC7A5ABCG2ABCB1CA12CA1 | |
| SCHEMBL28669756 | 0.81 | SLC7A5 (0.42) | SLC7A5ABCG2ABCB1CA12CA1 | |
| SCHEMBL2344130 | 0.80 | SLC7A5 (0.52) | SLC7A5CA12CA1CA2CA9 | |
| SCHEMBL2031607 | 0.79 | ALDH1A1 (0.41) | SLC7A5ABCG2ABCB1CA12CA1 | |
| SCHEMBL21056029 | 0.78 | SLC7A5 (0.44) | SLC7A5ABCG2ABCB1CA12CA1 | |
| SCHEMBL30437476 | 0.78 | SLC7A5 (0.44) | SLC7A5ABCG2ABCB1CA12CA1 | |
| SCHEMBL31188294 | 0.78 | CA12 (0.49) | SLC7A5CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113912617-A | Substituted tricycles and methods of use | 艾伯维公司 | 2022-01-11 | — | — | CN | disclosed |
| CN-108349930-B | Substituted tricycles and methods of use | 艾伯维公司 | 2021-10-29 | — | — | CN | disclosed |