SCHEMBL28664828

SCHEMBL28664828

O=C(O)c1cccc2[nH]c(=O)n(Cc3ccc(-c4ccccc4-c4noc(=O)[nH]4)cc3)c12

nearest known ligand 0.69

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 1/20 0.49
AGTR1 P30556 3/20 0.49
PPARG P37231 1/20 0.47
LTB4R2 Q9NPC1 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30539277 1.00 AGTR2 (0.49) AGTR2AGTR1PPARGLTB4R2
SCHEMBL30539225 1.00 AGTR2 (0.49) AGTR2AGTR1PPARGLTB4R2
SCHEMBL13465241 0.89 AGTR2 (0.54) AGTR2AGTR1PPARG
SCHEMBL18088504 0.84 AGTR2 (0.56) AGTR2
SCHEMBL18087887 0.83 AGTR2 (0.59) AGTR2
SCHEMBL4935797 0.83 AGTR1 (0.44) AGTR2AGTR1PPARGLTB4R2
SCHEMBL684043 0.82 AGTR2 (0.59) AGTR2
SCHEMBL683370 0.82 AGTR2 (0.61) AGTR2AGTR1PPARGLTB4R2
SCHEMBL9882910 0.82 AGTR2 (0.55) AGTR2
Azilsartan SCHEMBL167538 0.81 AGTR2 (0.72) AGTR2AGTR1PPARGLTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113466360-B Azilsartan 6 related substance detection method 珠海润都制药股份有限公司 2023-03-03 CN claimed
CN-113466360-A Azilsartan 6 related substance detection method 珠海润都制药股份有限公司 2021-10-01 CN claimed
CN-116807986-A Azilsartan amlodipine tablet and preparation method thereof 北京百奥药业有限责任公司 2023-09-29 CN disclosed