Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.50 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.50 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30084702 | 0.85 | CD274 (0.69) | CD274PDCD1PTGS1 | |
| SCHEMBL7107915 | 0.85 | CD274 (0.69) | CD274PDCD1PTGS1 | |
| SCHEMBL20539492 | 0.82 | CD274 (0.47) | CD274PDCD1TSHRALDH1A1 | |
| SCHEMBL1559894 | 0.80 | CYP2C19 (0.49) | SUCNR1PTGS2FFAR4CYP2C19SLC6A4 | |
| SCHEMBL13176495 | 0.76 | NPC1 (0.47) | CD274PDCD1SUCNR1PTGS2CYP2C19 | |
| SCHEMBL5981884 | 0.76 | FFAR4 (0.52) | CD274PDCD1SUCNR1PTGS2FFAR4 | |
| SCHEMBL30531243 | 0.76 | FFAR1 (0.42) | CD274PDCD1FFAR4SLC6A4SLC6A3 | |
| SCHEMBL6914998 | 0.75 | TSHR (0.38) | CD274PDCD1TSHRHSD17B10ALDH1A1 | |
| SCHEMBL28356514 | 0.73 | CD274 (0.44) | CD274PDCD1FFAR4NPC1TSHR | |
| SCHEMBL4456694 | 0.73 | SLC6A4 (0.42) | CD274PDCD1SUCNR1PTGS2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112920132-B | Small-molecule non-nucleoside compound serving as immunomodulator | 齐鲁师范学院 | 2023-08-15 | — | — | CN | disclosed |
| CN-112920132-A | Small molecule non-nucleoside compound as immunomodulator | 齐鲁师范学院 | 2021-06-08 | — | — | CN | disclosed |