Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 16/20 | 0.69 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.69 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30084702 | 1.00 | CD274 (0.69) | CD274PDCD1DPP4PTGS1EPHX1 | |
| SCHEMBL27976434 | 0.86 | CD274 (0.57) | CD274PDCD1DPP4PTGS1EPHX1 | |
| SCHEMBL20539492 | 0.85 | CD274 (0.47) | CD274PDCD1DPP4 | |
| SCHEMBL28664909 | 0.85 | CD274 (0.50) | CD274PDCD1PTGS1 | |
| Ammonia Solution, Strong SCHEMBL2967636 | 0.82 | CD274 (0.47) | CD274PDCD1DPP4PTGS1CYP2A6 | |
| SCHEMBL607544 | 0.82 | CD274 (0.71) | CD274PDCD1DPP4PTGS1EPHX1 | |
| SCHEMBL358303 | 0.82 | CD274 (1.00) | CD274PDCD1DPP4PTGS1EPHX1 | |
| SCHEMBL29558512 | 0.82 | CD274 (1.00) | CD274PDCD1DPP4PTGS1EPHX1 | |
| SCHEMBL83911 | 0.81 | DPP4 (0.60) | CD274PDCD1DPP4CYP2A6 | |
| SCHEMBL21153739 | 0.80 | CD274 (0.69) | CD274PDCD1DPP4PTGS1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946203-A | Glycyrrhetinic acid-gold complex and preparation method and application thereof | 南京中医药大学 | 2024-04-30 | — | — | CN | claimed |
| CN-103772151-B | A kind of preparation method of 2-methyl-3-phenyl benzil alcohol | JIANGSU LIANHUA TECHNOLOGY CO., LTD. (CN) | 2016-01-20 | — | — | CN | claimed |
| CN-102911093-B | Preparation method for sulfur fluorine oxime ether | HUNAN RES INST CHEMICAL IND | 2014-08-13 | — | — | CN | claimed |
| CN-103772151-A | Preparation method of 2-methyl-3-phenyl benzyl alcohol | JIANGSU LIANHUA TECHNOLOGY CO LTD | 2014-05-07 | — | — | CN | claimed |
| CN-102911093-A | Preparation method for sulfur fluorine oxime ether | HUNAN RES INST CHEMICAL IND | 2013-02-06 | — | — | CN | claimed |
| US-4473709-A | Pyrethroid intermediates and process | FMC CORPORATION (US) | 1984-09-25 | — | — | US | claimed |
| CN-117946203-A | Glycyrrhetinic acid-gold complex and preparation method and application thereof | 南京中医药大学 | 2024-04-30 | — | — | CN | disclosed |
| US-11952355-B2 | Method of preparing malononitrile oxime ether compound and intermediate compound | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2024-04-09 | — | — | US | disclosed |
| CN-111559981-B | Biphenyl-pyrimidine conjugate and preparation method and application thereof | 杭州庆正鸿科技有限公司 | 2023-08-01 | — | — | CN | disclosed |
| EP-3395795-B1 | MALONONITRILE OXIME ETHER COMPOUND AND USE THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) | 2023-07-19 | — | — | EP | disclosed |
| EP-3395795-B1 | MALONONITRILE OXIME ETHER COMPOUND AND USE THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) | 2023-07-19 | — | — | EP | disclosed |
| CN-113387840-B | PD-1/PD-L1 and HDACs double-target inhibitor, preparation method and application | 中国药科大学 | 2022-11-08 | — | — | CN | disclosed |
| CN-114276291-A | Process for preparing malononitrile oxime ether compounds and intermediate compounds | 沈阳中化农药化工研发有限公司 | 2022-04-05 | — | — | CN | disclosed |
| WO-2001096484-A1 | AQUEOUS COATING SUBSTANCES FOR IMPARTING A COLOUR AND/OR EFFECT AND USE THEREOF FOR PRODUCING DEFORMABLE LAMINATES FOR IMPARTING A COLOUR AND/OR EFFECT | BASF COATINGS AG (DE) | 2001-12-20 | — | — | WO | disclosed |
| US-H49-H | Process for producing 3-(2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethylcyclopropanecarboxylates | FMC CORPORATION (US) | 1986-04-01 | — | — | US | disclosed |
| EP-0125248-A1 | INSECTICIDAL SUBSTITUTED-BIPHENYLMETHYL OXIME ETHERS | FMC Corporation (US) | 1984-11-21 | — | — | EP | disclosed |
| US-4473709-A | Pyrethroid intermediates and process | FMC CORPORATION (US) | 1984-09-25 | — | — | US | disclosed |
| WO-1984001772-A1 | INSECTICIDAL SUBSTITUTED-BIPHENYLMETHYL OXIME ETHERS | FMC CORP (US) | 1984-05-10 | — | — | WO | disclosed |
| US-4434182-A | Insecticidal substituted-biphenylmethyl oxime ethers | FMC CORPORATION (US) | 1984-02-28 | — | — | US | disclosed |
| US-4180670-A | Amino pyridine derivatives | JOHN WYETH & BROTHER LIMITED (GB) | 1979-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11952355-B2 | Method of preparing malononitrile oxime ether compound and intermediate compound | CYP2E1, CYP3A4, POR | CD274 4682/4885PDCD1 4676/4885DPP4 1238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.