Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.58 |
| ▸ | PLK1 | P53350 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ICMT | O60725 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27851127 | 0.86 | CDC25A (0.62) | CDC25APLK1ALDH1A1LMNAMCL1 | |
| SCHEMBL28168045 | 0.83 | CDC25A (0.67) | CDC25APLK1ALDH1A1LMNAMCL1 | |
| SCHEMBL18180209 | 0.81 | CDC25A (0.63) | CDC25APLK1ALDH1A1LMNAMCL1 | |
| SCHEMBL3743075 | 0.80 | CDC25A (0.70) | CDC25APLK1ALDH1A1LMNAMCL1 | |
| SCHEMBL2051630 | 0.79 | ALDH1A1 (0.80) | CDC25APLK1ALDH1A1LMNAKMT2A | |
| SCHEMBL2465449 | 0.79 | CDC25A (0.68) | CDC25APLK1ALDH1A1LMNAMCL1 | |
| SCHEMBL29379289 | 0.79 | CDC25A (0.68) | CDC25APLK1ALDH1A1LMNAMCL1 | |
| SCHEMBL15747715 | 0.78 | CDC25A (0.80) | CDC25APLK1ALDH1A1LMNAMCL1 | |
| SCHEMBL2187777 | 0.78 | CDC25A (0.59) | CDC25APLK1ALDH1A1LMNAMCL1 | |
| SCHEMBL29376139 | 0.78 | CDC25A (0.67) | CDC25APLK1ALDH1A1LMNAMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110218206-B | Bisindolylmaleimide derivative and preparation method and application thereof | 中国海洋大学 | 2022-03-04 | — | — | CN | disclosed |
| CN-110526903-B | Bisindolylmaleimide derivative and preparation method and application thereof | 中国海洋大学 | 2021-12-10 | — | — | CN | disclosed |