Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.67 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.59 |
| ▸ | PLK1 | P53350 | 5/20 | 0.53 |
| ▸ | ICMT | O60725 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | CDK9 | P50750 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TERT | O14746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27851127 | 0.92 | CDC25A (0.62) | CDC25AMCL1PLK1ICMTSMN1; SMN2 | |
| SCHEMBL28665118 | 0.83 | CDC25A (0.58) | CDC25AMCL1PLK1ICMTALDH1A1 | |
| SCHEMBL28370235 | 0.83 | CDC25A (0.73) | CDC25AMCL1PLK1ICMTALDH1A1 | |
| SCHEMBL28840792 | 0.83 | CDC25A (0.73) | CDC25AMCL1PLK1ICMTALDH1A1 | |
| SCHEMBL15747729 | 0.82 | CDC25A (0.90) | CDC25AMCL1PLK1ICMTALDH1A1 | |
| SCHEMBL28968451 | 0.81 | CNR2 (0.60) | PLK1SMN1; SMN2ALDH1A1CNR1CNR2 | |
| SCHEMBL2429439 | 0.81 | CDC25A (0.97) | CDC25AMCL1PLK1ICMTALDH1A1 | |
| SCHEMBL2465449 | 0.80 | CDC25A (0.68) | CDC25AMCL1PLK1ICMTALDH1A1 | |
| SCHEMBL29379289 | 0.80 | CDC25A (0.68) | CDC25AMCL1PLK1ICMTALDH1A1 | |
| SCHEMBL15747697 | 0.80 | CDC25A (1.00) | CDC25AMCL1PLK1ICMTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107174581-B | Application of N-alkyl indole compounds in preparation of anti-HIV (human immunodeficiency Virus) medicines | 中国医学科学院药物研究所 | 2020-05-01 | — | — | CN | disclosed |
| CN-107151223-B | Application of N-alkyl indole compounds in preparation of anti-influenza virus drugs | 中国医学科学院药物研究所 | 2020-03-31 | — | — | CN | disclosed |
| CN-107151231-B | Indole compounds with antiviral activity | 中国医学科学院药物研究所 | 2020-03-27 | — | — | CN | disclosed |
| CN-107174581-A | Purposes of the one class N- alkyl-indol class compounds in inverase is prepared | 中国医学科学院药物研究所 | 2017-09-19 | — | — | CN | disclosed |
| CN-107151231-A | A class Benzazole compounds with antiviral activity | 中国医学科学院药物研究所 | 2017-09-12 | — | — | CN | disclosed |
| CN-107151223-A | Purposes of the one class N- alkyl-indol class compounds in anti-influenza virus medicament is prepared | 中国医学科学院药物研究所 | 2017-09-12 | — | — | CN | disclosed |