SCHEMBL28665161

SCHEMBL28665161

C=C(C)C(=O)NC(C)C(=C)NC(N)=O

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.39
CRBN Q96SW2 1/20 0.38
TDP1 Q9NUW8 1/20 0.36
RXFP1 Q9HBX9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4537746 0.79 TGFBR1 (0.44) TGFBR1TDP1RXFP1
SCHEMBL8377936 0.79 TGFBR1 (0.44) TGFBR1TDP1RXFP1
SCHEMBL10543946 0.74 TGFBR1 (0.47) TGFBR1TDP1RXFP1
SCHEMBL203009 0.74
SCHEMBL28609466 0.74 TGFBR1 (0.42) TGFBR1CRBNTDP1RXFP1
SCHEMBL5451737 0.74 CA14 (0.43) TGFBR1TDP1RXFP1
SCHEMBL5497463 0.74 CA14 (0.43) TGFBR1TDP1RXFP1
SCHEMBL28385316 0.73 TDP1 (0.36) TGFBR1TDP1RXFP1
SCHEMBL149929 0.73 TGFBR1 (0.55) TGFBR1RXFP1
SCHEMBL13952748 0.73 TGFBR1 (0.50) TGFBR1TDP1RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112292423-B Aqueous dispersions of multistage polymer particles and methods for their preparation 陶氏环球技术有限责任公司 2022-11-04 CN disclosed
CN-110997825-B Aqueous coating composition 陶氏环球技术有限责任公司 2021-11-26 CN disclosed