SCHEMBL5451737

SCHEMBL5451737

C=C(C)C(=O)NC(C)C(=O)OC

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA14 Q9ULX7 1/20 0.43
TGFBR1 P36897 1/20 0.42
ALDH1A1 P00352 2/20 0.41
TSHR P16473 5/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
MAPT P10636 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
RECQL P46063 1/20 0.37
KDM4E B2RXH2 1/20 0.36
HPGD P15428 1/20 0.36
RXFP1 Q9HBX9 1/20 0.35
MAPK1 P28482 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
BIRC2 Q13490 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5497463 1.00 CA14 (0.43) CA14TGFBR1ALDH1A1TSHRMEN1
SCHEMBL6016721 0.82 CA14 (0.46) CA14ALDH1A1TSHRMEN1KMT2A
SCHEMBL5490987 0.82 TGFBR1 (0.43) TGFBR1
SCHEMBL10029746 0.80 TGFBR1 (0.38) CA14TGFBR1ALDH1A1TSHRMEN1
SCHEMBL8377936 0.80 TGFBR1 (0.44) TGFBR1ALDH1A1TSHRKDM4ERXFP1
SCHEMBL4537746 0.80 TGFBR1 (0.44) TGFBR1ALDH1A1TSHRKDM4ERXFP1
SCHEMBL10543946 0.79 TGFBR1 (0.47) TGFBR1ALDH1A1TSHRKDM4ERXFP1
SCHEMBL7099645 0.79 CA12 (0.47) CA14TGFBR1ALDH1A1TSHRMEN1
SCHEMBL27555226 0.79 CA12 (0.47) CA14TGFBR1ALDH1A1TSHRMEN1
Potassium Ion SCHEMBL18139997 0.78 TGFBR1 (0.42) TGFBR1ALDH1A1RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3355706-B1 GUM BASES AND CHEWING GUMS USING THERMOSENSITIVE POLYMERS WRIGLEY W M JUN CO (US) 2020-11-04 EP claimed
US-20190110497-A1 GUM BASES AND CHEWING GUMS USING THERMOSENSITIVE POLYMERS WM. WRIGLEY JR. COMPANY 2019-04-18 US claimed
EP-3355706-A1 GUM BASES AND CHEWING GUMS USING THERMOSENSITIVE POLYMERS Wm. Wrigley Jr. Company (US) 2018-08-08 EP claimed
US-12533055-B2 Polymer materials SMITH & NEPHEW PLC (GB) 2026-01-27 US disclosed
US-11960038-B2 Radiation dosimetry gel and radiation dosimeter comprising same as material for measuring radiation dose RIKEN (JP) 2024-04-16 US disclosed
EP-3402450-B1 DEVICE AND KIT FOR INDICATING A PH AT A LOCUS SMITH & NEPHEW (GB) 2023-10-18 EP disclosed
US-20230172496-A1 POLYMER MATERIALS SMITH & NEPHEW (GB) 2023-06-08 US disclosed
US-11504033-B2 Polymer materials SMITH & NEPHEW PLC (GB) 2022-11-22 US disclosed
US-11471076-B2 Device and kit for indicating a pH at a locus SMITH & NEPHEW PLC (GB) 2022-10-18 US disclosed
US-20220221594-A1 RADIATION DOSIMETRY GEL AND RADIATION DOSIMETER COMPRISING SAME AS MATERIAL FOR MEASURING RADIATION DOSE RIKEN (JP) 2022-07-14 US disclosed
WO-2021162110-A1 GEL DOSIMETER FOR MEASURING RADIATION DOSES 学校法人北里研究所 2021-08-19 WO disclosed
EP-3246731-A1 RADIATION DOSIMETRY GEL AND RADIATION DOSIMETER PROVIDED WITH SAME AS MATERIAL FOR MEASURING RADIATION DOSE Riken (JP) 2017-11-22 EP disclosed
US-20070110784-A1 Thermally reversible implant RIMON THERAPEUTICS LTD. (CA) 2007-05-17 US disclosed
US-7193007-B2 Polyethylene glycol/poly(N-iso-propylacrylamide) block copolymers; time-release agents; in-situ implants CHENG YU-LING 2007-03-20 US disclosed
US-7160931-B2 Thermally reversible implant and filler CHENG YU-LING 2007-01-09 US disclosed
US-20050020719-A1 Environment responsive gelling copolymer CHENG YU-LING (CA) 2005-01-27 US disclosed
WO-2004096309-A1 THERMALLY REVERSIBLE IMPLANT RIMON THERAPEUTICS LTD. (CA) 2004-11-11 WO disclosed
US-20040029994-A1 Thermally reversible implant and filler CHENG YU-LING (CA) 2004-02-12 US disclosed
EP-1272562-A1 ENVIRONMENT RESPONSIVE GELLING COPOLYMER CHENG, Yu-Ling (CA) 2003-01-08 EP disclosed
WO-2001068768-A1 ENVIRONMENT RESPONSIVE GELLING COPOLYMER CHENG YU LING (CA) 2001-09-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12533055-B2 Polymer materials MASTL, PRKG2, PRKG1 CA14 555/4885TGFBR1 2588/4885ALDH1A1 2382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.