Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL28665355

Clc1cccc(C2CCNCC2)n1.O=C(O)C(F)(F)F

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 1/20 0.43
CDK2 P24941 1/20 0.43
CDK5 Q00535 1/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
CYP1A2 P05177 1/20 0.43
PRCP P42785 1/20 0.39
HTR2C P28335 5/20 0.38
HRH4 Q9H3N8 1/20 0.37
HRH3 Q9Y5N1 1/20 0.37
PARP1 P09874 1/20 0.36
HTR3E A5X5Y0 1/20 0.36
HTR3B O95264 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HTR3A P46098 1/20 0.36
HTR3D Q70Z44 1/20 0.36
HTR3C Q8WXA8 1/20 0.36
POLB P06746 1/20 0.36
SLC18A3 Q16572 1/20 0.36
SIGMAR1 Q99720 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30174508 0.85 MEN1 (0.54) MEN1KMT2ACYP1A2HTR2CHRH4
SCHEMBL24338764 0.85 MEN1 (0.54) MEN1KMT2ACYP1A2HTR2CHRH4
Hydrochloric Acid SCHEMBL20266524 0.84 MEN1 (0.53) MEN1KMT2ACYP1A2HTR2CHRH4
Bicarbonate SCHEMBL19583807 0.79 POLB (0.41) MEN1KMT2ACYP1A2HTR3EHTR3B
Trifluoroacetic Acid SCHEMBL9024551 0.78 SLC18A3 (0.41) HTR2CHRH4HRH3SLC18A3SIGMAR1
Trifluoroacetic Acid SCHEMBL4451796 0.78 MEN1 (0.46) MEN1KMT2AHTR2CPOLBSIGMAR1
Trifluoroacetic Acid SCHEMBL15167690 0.75 TSHR (0.48) KMT2AALDH1A1
Trifluoroacetic Acid SCHEMBL30404349 0.75 GLP1R (0.42)
Trifluoroacetic Acid SCHEMBL25272721 0.75 GLP1R (0.42)
Trifluoroacetic Acid SCHEMBL21274845 0.74 TRPC6 (0.40) CDK4CDK2CDK5HTR2CHRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113493447-B GLP-1 receptor agonists 轩竹(北京)医药科技有限公司 2024-06-11 CN disclosed
CN-113493447-A GLP-1 receptor agonists 山东轩竹医药科技有限公司 2021-10-12 CN disclosed