SCHEMBL28665397

SCHEMBL28665397

COc1c(C)nn(C)c(=O)c1-c1c(-c2ccc(OCc3ccccc3)cc2)oc2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 7/20 0.44
NPC1 O15118 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
ATM Q13315 1/20 0.44
KDM4E B2RXH2 3/20 0.43
ALDH1A1 P00352 3/20 0.43
CYP19A1 P11511 2/20 0.42
PTPN1 P18031 1/20 0.42
PKM P14618 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
FAAH O00519 1/20 0.41
MGLL Q99685 1/20 0.41
ABCB1 P08183 1/20 0.41
ABCC1 P33527 1/20 0.41
CYP11B1 P15538 1/20 0.41
CYP11B2 P19099 1/20 0.41
PPARG P37231 1/20 0.41
MAPT P10636 2/20 0.40
HPGD P15428 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28666647 0.88 ABCG2 (0.45) ABCG2NPC1KDM4EALDH1A1CYP19A1
SCHEMBL22499952 0.86 ABCG2 (0.45) ABCG2NPC1L3MBTL1ATMKDM4E
SCHEMBL10769734 0.78 ABCG2 (0.72) ABCG2NPC1L3MBTL1ATMKDM4E
SCHEMBL28659825 0.77 ALDH1A1 (0.43) ABCG2NPC1KDM4EALDH1A1CYP19A1
SCHEMBL15935630 0.75 NPC1 (0.45) NPC1L3MBTL1ALDH1A1PKMRAB9A
SCHEMBL29385131 0.73 MAOB (0.41) NPC1L3MBTL1KDM4EALDH1A1CYP19A1
SCHEMBL15935708 0.73 NPC1 (0.43) NPC1L3MBTL1PKMRAB9ASMN1; SMN2
SCHEMBL28565701 0.72 ABCG2 (0.69) ABCG2NPC1L3MBTL1ATMKDM4E
SCHEMBL28665391 0.70 MEN1 (0.42) NPC1L3MBTL1KDM4EALDH1A1CYP19A1
SCHEMBL17523228 0.68 ABCG2 (0.58) ABCG2NPC1KDM4EALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113825398-A Pyridazinone compounds and herbicides 日产化学株式会社 2021-12-21 CN disclosed