Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 8/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28565701 | 0.91 | ABCG2 (0.69) | ABCG2KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL4167435 | 0.85 | ABCG2 (0.70) | ABCG2KDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL4650702 | 0.84 | ABCG2 (1.00) | ABCG2KDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL2395500 | 0.84 | KDM4E (0.67) | ABCG2KDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL972002 | 0.83 | KDM4E (0.68) | ABCG2KDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL23260274 | 0.83 | ABCG2 (0.72) | ABCG2KDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL20169801 | 0.83 | ABCG2 (0.59) | ABCG2KDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL30025454 | 0.83 | ABCG2 (0.72) | ABCG2KDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL2396986 | 0.83 | ABCG2 (0.55) | ABCG2KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL253523 | 0.83 | ABCG2 (1.00) | ABCG2KDM4EALDH1A1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233105-A1 | Therapeutical compositions based on 3-alkoxyflavone derivatives and derivatives of 3-alkoxyflavones | INSTITUT PASTEUR (FR) | 1987-08-19 | — | — | EP | disclosed |