Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8579724 | 0.80 | MAPT (0.35) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL21681150 | 0.80 | TDP1 (0.46) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL8581574 | 0.80 | TDP1 (0.44) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL8581078 | 0.80 | TSHR (0.36) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL8580495 | 0.78 | ALDH1A1 (0.38) | ALDH1A1TDP1MEN1KMT2ATSHR | |
| SCHEMBL30659890 | 0.77 | MEN1 (0.47) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL7777578 | 0.76 | PDE10A (0.50) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL21712222 | 0.72 | PI4KA (0.36) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL15220550 | 0.71 | TDP1 (0.56) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL11684574 | 0.69 | PI4KA (0.34) | MAPTALDH1A1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113912542-A | Method for directly ammoniating nitro nitrogen heterocyclic compound | 南京理工大学 | 2022-01-11 | — | — | CN | disclosed |