Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TXNRD1 | Q16881 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.35 |
| ▸ | TUBB | P07437 | 2/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8581574 | 0.81 | TDP1 (0.44) | ALDH1A1TDP1HTTKMT2AMEN1 | |
| SCHEMBL2400631 | 0.79 | MEN1 (0.54) | ALDH1A1TDP1HTTKMT2AMEN1 | |
| SCHEMBL21681150 | 0.78 | TDP1 (0.46) | ALDH1A1TDP1HTTKMT2AMEN1 | |
| SCHEMBL8579724 | 0.78 | MAPT (0.35) | ALDH1A1TDP1HTTKMT2AMEN1 | |
| SCHEMBL28666281 | 0.78 | MAPT (0.43) | ALDH1A1TDP1HTTKMT2AMEN1 | |
| SCHEMBL8581078 | 0.77 | TSHR (0.36) | ALDH1A1TDP1HTTKMT2AMEN1 | |
| SCHEMBL7777578 | 0.73 | PDE10A (0.50) | ALDH1A1TDP1HTTKMT2AMEN1 | |
| SCHEMBL25347148 | 0.73 | NQO2 (0.44) | ALDH1A1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL20897727 | 0.69 | PDE10A (0.61) | ALDH1A1TDP1HTTKMT2AMEN1 | |
| SCHEMBL358770 | 0.68 | TDP1 (0.61) | ALDH1A1TDP1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998023612-A1 | 2-IMIDAZOLINYLAMINOBENZOTHIAZOLE COMPOUNDS USEFUL AS ALPHA-2 ADRENOCEPTOR AGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 1998-06-04 | — | — | WO | disclosed |