Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Biphenyl. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8926574 | 0.94 | GPR3 (0.30) | — | |
| Biphenyl SCHEMBL2865842 | 0.85 | — | — | |
| Biphenyl SCHEMBL2863899 | 0.85 | — | — | |
| Biphenyl SCHEMBL2856365 | 0.83 | NPC1 (0.33) | — | |
| Biphenyl SCHEMBL2869399 | 0.83 | NPC1 (0.33) | — | |
| Biphenyl SCHEMBL398518 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL3645160 | 0.80 | BCHE (0.32) | — | |
| Hydrochloric Acid SCHEMBL3645157 | 0.80 | BCHE (0.32) | — | |
| Biphenyl SCHEMBL400845 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL5858105 | 0.79 | MAPT (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1661921-B1 | Synthetic lubricating oil and lubricating oil composition thereof | MITSUI CHEMICALS INC (JP) | 2019-07-17 | — | — | EP | disclosed |
| US-7795194-B2 | Synthetic lubricating oil and lubricating oil composition | MITSUI CHEMICALS, INC. (JP) | 2010-09-14 | — | — | US | disclosed |
| US-7393965-B2 | Crosslinked metallocene compound for olefin polymerization and method of polymerizing olefin with the same | MITSUI CHEMICALS, INC. (JP) | 2008-07-01 | — | — | US | disclosed |
| US-20060161013-A1 | Crosslinked metallocene compound for olefin polymerization and method of polymerizing olefin with the same | MITSUI CHEMICALS, INC. (JP) | 2006-07-20 | — | — | US | disclosed |
| US-20060116303-A1 | decene-ethylene copolymer, zirconium, titanium or hafnium fluorene-containing complexes, organometallics; improved high thermal oxidation stability, viscosity index, low-temperature viscosity properties and shear stability | MITSUI CHEMICALS, INC. (JP) | 2006-06-01 | — | — | US | disclosed |
| EP-1661921-A1 | Synthetic lubricating oil and lubricating oil composition thereof | Mitsui Chemicals, Inc. (JP) | 2006-05-31 | — | — | EP | disclosed |
| CN-1684968-A | Crosslinked metallocene compound for olefin polymerization and olefin polymerization method using the same | MITSUI CHEMICALS INC (JP) | 2005-10-19 | — | — | CN | disclosed |