Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27931718 | 0.80 | TSHR (0.55) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL29094948 | 0.75 | FABP4 (0.54) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL16009269 | 0.75 | BRD4 (0.49) | LMNAALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL29955686 | 0.75 | BRD4 (0.49) | LMNAALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL6990716 | 0.74 | FABP4 (0.47) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL14134529 | 0.74 | MAPT (0.56) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4957139 | 0.73 | FABP4 (0.56) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL129359 | 0.73 | TSHR (0.59) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL29402736 | 0.73 | TSHR (0.59) | LMNAMAPTALDH1A1MEN1KMT2A | |
| Dimethyl Phthalate SCHEMBL3686830 | 0.73 | TSHR (0.63) | LMNAMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113788955-B | Metal organic framework catalyst, preparation method and application | 华中科技大学同济医学院附属协和医院 | 2022-09-23 | — | — | CN | disclosed |
| CN-113957094-A | Delivery system with enhanced gene editing efficiency, preparation method and application | 华中科技大学同济医学院附属协和医院 | 2022-01-21 | — | — | CN | disclosed |
| CN-113788955-A | Metal organic framework catalyst, preparation method and application | 华中科技大学同济医学院附属协和医院 | 2021-12-14 | — | — | CN | disclosed |