Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 6/20 | 0.47 |
| ▸ | FABP3 | P05413 | 4/20 | 0.47 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29094948 | 0.81 | FABP4 (0.54) | FABP4FABP3FABP5SLC6A4SLC6A3 | |
| SCHEMBL7638449 | 0.79 | FABP4 (0.55) | FABP4FABP3FABP5SLC6A4SLC6A3 | |
| SCHEMBL27967782 | 0.78 | FABP4 (0.50) | FABP4FABP3FABP5MEN1KMT2A | |
| SCHEMBL7946301 | 0.78 | ACLY (0.44) | SLC6A4SLC6A3LMNAPLA2G2AMEN1 | |
| SCHEMBL27467245 | 0.78 | TSHR (0.57) | SLC6A4SLC6A3LMNAMAPTALDH1A1 | |
| SCHEMBL27931718 | 0.77 | TSHR (0.55) | LMNAMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL6255108 | 0.75 | SLC6A3 (0.55) | SLC6A4SLC6A3LMNAMEN1MAPT | |
| SCHEMBL14134529 | 0.74 | MAPT (0.56) | SLC6A4SLC6A3LMNAPLA2G2AMEN1 | |
| SCHEMBL28668124 | 0.74 | LMNA (0.45) | SLC6A3LMNAMEN1MAPTKMT2A | |
| SCHEMBL30478408 | 0.74 | LMNA (0.49) | FABP4FABP3FABP5LMNAPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1276726-A2 | SUBSTITUTED PHENYL FARNESYLTRANSFERASE INHIBITORS | Abbott Laboratories (US) | 2003-01-22 | — | — | EP | disclosed |
| WO-2001081316-A2 | SUBSTITUTED PHENYL FARNESYLTRANSFERASE INHIBITORS | ABBOTT LABORATORIES (US) | 2001-11-01 | — | — | WO | disclosed |