Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | KIF20A | O95235 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28692843 | 0.98 | MAPT (0.45) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL7575165 | 0.79 | GRIN2D (0.41) | ALDH1A1HTTTDP1GRIN2DGRIN3B | |
| SCHEMBL21430771 | 0.79 | ALDH1A1 (0.46) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL11350306 | 0.79 | ALDH1A1 (0.62) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL3366325 | 0.78 | MCL1 (0.60) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL3951201 | 0.78 | MCL1 (0.60) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL987696 | 0.78 | MAPT (0.77) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL4879813 | 0.77 | MAPT (0.70) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL10386359 | 0.77 | MCL1 (0.69) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28459287 | 0.77 | MAPT (0.56) | MAPTMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113880745-A | Preparation method of trolepril | 山东亿嘉农化有限公司 | 2022-01-04 | — | — | CN | claimed |
| CN-113880745-A | Preparation method of trolepril | 山东亿嘉农化有限公司 | 2022-01-04 | — | — | CN | disclosed |
| CN-113880745-A | Preparation method of trolepril | 山东亿嘉农化有限公司 | 2022-01-04 | — | — | CN | disclosed |