Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.70 |
| ▸ | GAA | P10253 | 3/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | ATM | Q13315 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.64 |
| ▸ | HPGD | P15428 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 7/20 | 0.61 |
| ▸ | RECQL | P46063 | 4/20 | 0.61 |
| ▸ | BLM | P54132 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32688074 | 0.95 | MAPT (0.64) | MAPTALDH1A1GAAHTTATM | |
| SCHEMBL4878079 | 0.82 | MAPT (0.70) | MAPTALDH1A1GAAHTTATM | |
| SCHEMBL27294438 | 0.82 | MCL1 (0.69) | MAPTALDH1A1GAAKMT2ATDP1 | |
| SCHEMBL32688435 | 0.82 | MAPT (0.70) | MAPTALDH1A1GAAHTTATM | |
| SCHEMBL4879772 | 0.82 | MAPT (0.70) | MAPTALDH1A1GAAHTTATM | |
| SCHEMBL10386359 | 0.82 | MCL1 (0.69) | MAPTALDH1A1GAAKMT2ATDP1 | |
| SCHEMBL19928344 | 0.81 | MAPT (0.69) | MAPTALDH1A1GAAHTTATM | |
| SCHEMBL8483397 | 0.81 | ALDH1A1 (0.65) | MAPTALDH1A1GAAHTTATM | |
| SCHEMBL32687992 | 0.81 | ALDH1A1 (0.52) | MAPTALDH1A1GAAHTTATM | |
| SCHEMBL32688162 | 0.79 | MAPT (0.66) | MAPTALDH1A1GAAHTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | ORSOBIO INC (US) | 2026-03-19 | — | — | US | disclosed |
| US-20080171440-A1 | Pre-polishing treatment solution for interconnect substrate, polishing method, and method and apparatus for manufacturing interconnect substrate | EBARA CORPORATION (JP) | 2008-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | CPT1B, CBR1, MUSK | MAPT 4018/4885ALDH1A1 290/4885GAA 1309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.