SCHEMBL5401290

SCHEMBL5401290

CCC(C)c1ccc2ccccc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UGT2B7 P16662 1/20 0.59
CYP1A2 P05177 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
CYP2D6 P10635 1/20 0.50
TSHR P16473 1/20 0.50
HIF1A Q16665 1/20 0.50
USP2 O75604 1/20 0.47
ALDH1A1 P00352 1/20 0.47
GAA P10253 1/20 0.47
PKM P14618 1/20 0.47
HPGD P15428 1/20 0.47
ALOX15 P16050 1/20 0.47
HSD17B10 Q99714 1/20 0.47
CYP2A6 P11509 1/20 0.47
AOC3 Q16853 1/20 0.46
ATM Q13315 1/20 0.46
HDAC4 P56524 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC8 Q9BY41 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16684715 1.00 UGT2B7 (0.59) UGT2B7CYP1A2MEN1KMT2ACYP2D6
SCHEMBL2491242 0.94 UGT2B7 (0.52) UGT2B7CYP1A2MEN1KMT2ACYP2D6
SCHEMBL9167387 0.91 ALDH1A1 (0.53) UGT2B7TSHRUSP2ALDH1A1GAA
SCHEMBL3725681 0.87 ALDH1A1 (0.50) UGT2B7TSHRUSP2ALDH1A1GAA
SCHEMBL3727201 0.87 ALDH1A1 (0.50) UGT2B7TSHRUSP2ALDH1A1GAA
SCHEMBL19164262 0.86 UGT2B7 (0.58) UGT2B7CYP1A2MEN1KMT2ACYP2D6
SCHEMBL11051116 0.84 UGT2B7 (0.55) UGT2B7CYP1A2MEN1KMT2ACYP2D6
SCHEMBL11998991 0.83 SLC7A5 (0.47) UGT2B7CYP1A2MEN1KMT2ACYP2D6
SCHEMBL11999024 0.83 MTNR1A (0.43) UGT2B7CYP2D6AOC3HDAC4HDAC2
SCHEMBL12299095 0.82 UGT2B7 (0.44) UGT2B7CYP1A2MEN1KMT2ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102260134-A Preparation method of 2-sec-butylnaphthalene 2011-11-30 CN claimed
JP-52106852-A None JP disclosed
CN-114534787-B Gas-phase dehydrogenation catalyst and method for isopentenol 万华化学集团股份有限公司 2023-12-19 CN disclosed
US-20230375928-A1 Sulfonium-Salt-Type Polymerizable Monomer, Polymer Photoacid Generator, Base Rein, Resist Composition, And Patterning Process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-23 US disclosed
EP-3063154-B1 CROSS-COUPLING OF UNACTIVATED SECONDARY BORONIC ACIDS UNIV ILLINOIS (US) 2023-08-30 EP disclosed
CN-111013609-B Metal oxide super acidic catalyst, preparation method and application thereof 中国石油化工股份有限公司 2023-04-07 CN disclosed
CN-111013609-A Metal oxide super acidic catalyst, preparation method and application thereof 中国石油化工股份有限公司 2020-04-17 CN disclosed
US-10570153-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2020-02-25 US disclosed
US-20190033716-A1 SULFONIUM SALT, POLYMER, RESIST COMPOSITION, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2019-01-31 US disclosed
US-10072028-B2 Cross-coupling of unactivated secondary boronic acids THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2018-09-11 US disclosed
EP-0484319-A1 A process of producing isopropylnaphthols MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-05-06 EP disclosed
EP-0440250-A2 Method of preparing alkylnaphthalene compounds NIPPON SHOKUBAI CO., LTD. (JP) 1991-08-07 EP disclosed
US-4906790-A Method of oxidizing secondary alkyl substituted naphtalenes and a process of producing isopropylnaphthols MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-03-06 US disclosed
CN-1003786-B Acylation of naphthalene 赛拉尼斯公司 1989-04-05 CN disclosed
EP-0308133-A1 A method of oxidising secondary alkyl substituted naphthalenes MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-03-22 EP disclosed
US-4783557-A Processes for preparing hydroxynaphthalenes MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-11-08 US disclosed
CN-86101420-A The acidylate of naphthalene 1986-11-12 CN disclosed
EP-0196805-A1 Acylation of naphthalenes CELANESE CORPORATION (US) 1986-10-08 EP disclosed
US-4593125-A In anhydrous hydrogen fluoride CELANESE CORPORATION (US) 1986-06-03 US disclosed
JP-S52106852-A BETA-SECONDARY-BUTYLNAPHTHALENES AGENCY OF IND SCIENCE & TECHNOL 1977-09-07 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10570153-B2 Benzodiazepine derivatives as RSV inhibitors GABRA5, GABRA1, GABBR2 UGT2B7 139/4885CYP1A2 58/4885MEN1 3463/4885
US-20190033716-A1 SULFONIUM SALT, POLYMER, RESIST COMPOSITION, AND PATTERNING PROCESS SMC4, SMCHD1, SMC3 UGT2B7 3209/4885CYP1A2 4863/4885MEN1 3961/4885
US-10072028-B2 Cross-coupling of unactivated secondary boronic acids BOLA2; BOLA2B, BLVRB, CD79B UGT2B7 226/4885CYP1A2 1283/4885MEN1 449/4885
US-20230375928-A1 Sulfonium-Salt-Type Polymerizable Monomer, Polymer Photoacid Generator, Base Rein, Resist Composition, And Patterning Process NAF1, RALA, RSU1 UGT2B7 4327/4885CYP1A2 3948/4885MEN1 3472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.