SCHEMBL28668447

SCHEMBL28668447

CSc1c(C)c(F)c(F)c(F)c1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22909568 0.79
SCHEMBL23793708 0.73 CES2 (0.31)
SCHEMBL28886977 0.73
SCHEMBL11131664 0.71 NOTUM (0.31)
SCHEMBL8025181 0.71
SCHEMBL107738 0.71
SCHEMBL10935805 0.71
SCHEMBL18920790 0.70 CES2 (0.32)
SCHEMBL13170369 0.70
SCHEMBL8846941 0.70 CES2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117865771-A Synthesis method of 2, 3-dichloro benzotrifluoride 上海泰初化工技术有限公司 2024-04-12 CN disclosed
CN-117820176-A Sulfoxide-based benzotrifluoride compound 上海泰初化工技术有限公司 2024-04-05 CN disclosed
CN-117820180-A Sulfonyl trifluoro toluene compound 上海泰初化工技术有限公司 2024-04-05 CN disclosed
CN-109790109-B Process for preparing 3-alkylthio-2-chloro-N- (1-alkyl-1H-tetrazol-5-yl) -4-trifluoromethylbenzamides 拜耳作物科学股份公司 2021-10-22 CN disclosed