Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK4 | Q16654 | 1/20 | 0.54 |
| ▸ | GRM1 | Q13255 | 11/20 | 0.54 |
| ▸ | GRM5 | P41594 | 11/20 | 0.54 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.48 |
| ▸ | KIT | P10721 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19703165 | 0.86 | PDK4 (0.53) | PDK4GRM1GRM5NAMPTGPR119 | |
| SCHEMBL31283668 | 0.85 | PDK4 (0.52) | PDK4GRM1GRM5NAMPTGPR119 | |
| SCHEMBL30779416 | 0.85 | PDK4 (0.52) | PDK4GRM1GRM5NAMPTGPR119 | |
| SCHEMBL1061832 | 0.85 | PDK4 (0.52) | PDK4GRM1GRM5NAMPTGPR119 | |
| SCHEMBL12892530 | 0.84 | GRM5 (0.56) | PDK4GRM1GRM5NAMPTGPR119 | |
| SCHEMBL24671087 | 0.83 | PDK4 (0.50) | PDK4GRM1GRM5NAMPTGPR119 | |
| SCHEMBL28672683 | 0.83 | GPR119 (0.52) | PDK4GRM1GRM5NAMPTGPR119 | |
| SCHEMBL3460339 | 0.83 | PDK4 (0.53) | PDK4GRM1GRM5NAMPTGPR119 | |
| SCHEMBL15376949 | 0.83 | PDK4 (0.50) | PDK4GRM1GRM5NAMPTGPR119 | |
| SCHEMBL8912847 | 0.81 | NAMPT (0.63) | PDK4GRM1GRM5NAMPTGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113735825-B | 1,2,3, 6-Tetrahydropyridine compound and preparation method and application thereof | 成都康弘药业集团股份有限公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-113735825-A | 1,2,3, 6-tetrahydropyridine compound and preparation method and application thereof | 成都康弘药业集团股份有限公司 | 2021-12-03 | — | — | CN | disclosed |