Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK4 | Q16654 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | GRM1 | Q13255 | 11/20 | 0.47 |
| ▸ | GRM5 | P41594 | 11/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28668463 | 0.83 | PDK4 (0.54) | PDK4HTR6GRM1GRM5GPR119 | |
| SCHEMBL19703165 | 0.82 | PDK4 (0.53) | PDK4HTR6GRM1GRM5GPR119 | |
| SCHEMBL31283668 | 0.81 | PDK4 (0.52) | PDK4HTR6GRM1GRM5GPR119 | |
| SCHEMBL30779416 | 0.81 | PDK4 (0.52) | PDK4HTR6GRM1GRM5GPR119 | |
| SCHEMBL1061832 | 0.81 | PDK4 (0.52) | PDK4HTR6GRM1GRM5GPR119 | |
| SCHEMBL24671087 | 0.79 | PDK4 (0.50) | PDK4HTR6GRM1GRM5GPR119 | |
| SCHEMBL28672683 | 0.79 | GPR119 (0.52) | PDK4HTR6GRM1GRM5GPR119 | |
| SCHEMBL21404004 | 0.79 | PDK4 (0.58) | PDK4HTR6GRM1GRM5NAMPT | |
| SCHEMBL12892530 | 0.78 | GRM5 (0.56) | PDK4HTR6GRM1GRM5GPR119 | |
| SCHEMBL3463072 | 0.77 | ITGB1 (0.53) | PDK4HTR6GRM1GRM5GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010146236-A1 | UREA SUBSTITUTED SULPHONAMIDE DERIVATIVES | BIOTIE THERAPIES CORP. (FI) | 2010-12-23 | — | — | WO | disclosed |