Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 12/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 12/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | HTR2B | P41595 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18212477 | 1.00 | PRMT5 (0.45) | PRMT5WDR77NAMPTHDAC4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL18205144 | 0.99 | PRMT5 (0.44) | PRMT5WDR77NAMPTHDAC4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL18205147 | 0.99 | PRMT5 (0.44) | PRMT5WDR77NAMPTHDAC4SIGMAR1 | |
| SCHEMBL18212476 | 0.88 | NAMPT (0.49) | PRMT5WDR77NAMPTHDAC4SIGMAR1 | |
| SCHEMBL18417276 | 0.82 | NAMPT (0.49) | PRMT5WDR77NAMPTHDAC4SIGMAR1 | |
| SCHEMBL17377256 | 0.80 | PRMT5 (0.50) | PRMT5WDR77CARM1 | |
| SCHEMBL17377259 | 0.80 | PRMT5 (0.50) | PRMT5WDR77CARM1 | |
| SCHEMBL805471 | 0.80 | SIGMAR1 (0.46) | PRMT5WDR77NAMPTSIGMAR1 | |
| SCHEMBL28655189 | 0.80 | CARM1 (0.57) | PRMT5WDR77CARM1 | |
| SCHEMBL18212446 | 0.80 | CARM1 (0.57) | PRMT5WDR77CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735088-B | Histone deacetylase inhibitors, compositions and methods of use thereof | CHDI基金会股份有限公司 | 2021-11-02 | — | — | CN | disclosed |