SCHEMBL2866864

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2858985	0.86	GAA (0.60)	MAPK1MAPK3TTKCSNK1D
	SCHEMBL2859764	0.86	MAPK1 (0.59)	MAPK1MAPK3TTKCSNK1D
	SCHEMBL2864841	0.84	MAPK1 (0.67)	MAPK1MAPK3TTK
	SCHEMBL12907350	0.82	MAPK1 (0.61)	MAPK1MAPK3TTK
	SCHEMBL11626565	0.81	NPC1 (0.81)	NPC1
	SCHEMBL8259091	0.80	MAP3K5 (0.53)	MAPK1MAPK3TTKCSNK1D
	SCHEMBL922525	0.78	MAPK1 (0.74)	MAPK1MAPK3TTKNPC1
	SCHEMBL2860189	0.77	MAPK1 (0.56)	MAPK1MAPK3TTKCSNK1D
	SCHEMBL5377830	0.76	MAPK1 (0.68)	MAPK1MAPK3TTKCSNK1D
	SCHEMBL13373433	0.76	FLT3 (0.59)	MAPK1MAPK3TTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.