SCHEMBL2858985

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2866864	0.86	MAPK1 (0.74)	MAPK3MAPK1TTKCSNK1D
	SCHEMBL2859764	0.83	MAPK1 (0.59)	GAAMAPK3MAPK1TTKALDH1A1
	SCHEMBL2864841	0.82	MAPK1 (0.67)	GAAMAPK3MAPK1L3MBTL1TTK
	SCHEMBL12907350	0.80	MAPK1 (0.61)	GAAMAPK3MAPK1ROCK2L3MBTL1
	SCHEMBL5334343	0.80	MMP13 (0.79)	GAAROCK2L3MBTL1USP2ALDH1A1
	SCHEMBL2868742	0.80	TTK (0.57)	GAAMAPK3MAPK1ROCK2TTK
	SCHEMBL12907153	0.79	SMN1; SMN2 (0.67)	ROCK2USP2ALDH1A1ROCK1CYP3A4
	SCHEMBL12191106	0.79	GAA (0.65)	GAAROCK2L3MBTL1USP2ALDH1A1
	SCHEMBL2858848	0.78	ROCK2 (0.59)	ROCK2ROCK1CYP3A4SMN1; SMN2AURKA
	SCHEMBL8259091	0.78	MAP3K5 (0.53)	MAPK3MAPK1ROCK2L3MBTL1TTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.