Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28668671 | 1.00 | SLC18A3 (0.45) | SLC18A3POLBNPC1NPSR1MEN1 | |
| SCHEMBL28650984 | 0.80 | NPSR1 (0.44) | SLC18A3POLBNPC1NPSR1MEN1 | |
| SCHEMBL28656457 | 0.78 | POLB (0.48) | POLBNPC1NPSR1 | |
| SCHEMBL28656456 | 0.78 | POLB (0.48) | POLBNPC1NPSR1 | |
| SCHEMBL28670698 | 0.77 | ALDH1A1 (0.42) | POLBNPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL28670700 | 0.77 | ALDH1A1 (0.42) | POLBNPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL28993898 | 0.75 | MEN1 (0.55) | MEN1KMT2A | |
| SCHEMBL18212452 | 0.75 | SLC18A3 (0.44) | SLC18A3 | |
| SCHEMBL18212456 | 0.74 | SLC18A3 (0.46) | SLC18A3ALDH1A1 | |
| SCHEMBL18205240 | 0.74 | HDAC4 (0.52) | SLC18A3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735088-B | Histone deacetylase inhibitors, compositions and methods of use thereof | CHDI基金会股份有限公司 | 2021-11-02 | — | — | CN | disclosed |