Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28656457 | 1.00 | POLB (0.48) | POLBCARM1USP2SMN1; SMN2NPC1 | |
| SCHEMBL28654413 | 0.90 | CARM1 (0.51) | POLBCARM1 | |
| SCHEMBL28654411 | 0.90 | CARM1 (0.51) | POLBCARM1 | |
| SCHEMBL28928596 | 0.79 | DRD2 (0.44) | POLBCARM1USP2SMN1; SMN2NPC1 | |
| SCHEMBL28668671 | 0.78 | SLC18A3 (0.45) | POLBNPC1NPSR1 | |
| SCHEMBL28668669 | 0.78 | SLC18A3 (0.45) | POLBNPC1NPSR1 | |
| SCHEMBL28654086 | 0.73 | DPP8 (0.57) | DPP8DPP9DPP7DPP4 | |
| SCHEMBL28654088 | 0.73 | DPP8 (0.57) | DPP8DPP9DPP7DPP4 | |
| SCHEMBL18212435 | 0.72 | CARM1 (0.51) | CARM1DPP8DPP9DPP7DPP4 | |
| SCHEMBL29563547 | 0.72 | CARM1 (0.61) | CARM1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735088-B | Histone deacetylase inhibitors, compositions and methods of use thereof | CHDI基金会股份有限公司 | 2021-11-02 | — | — | CN | disclosed |