Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | PTPRA | P18433 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782825 | 0.86 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2CYP1A2CYP2D6MAPT | |
| SCHEMBL8310726 | 0.84 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2CYP1A2CYP2D6MAPT | |
| SCHEMBL9110496 | 0.84 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2CYP1A2CYP2D6MAPT | |
| SCHEMBL27511050 | 0.83 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2CYP1A2CYP2D6MAPT | |
| SCHEMBL2499727 | 0.83 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2CYP1A2CYP2D6MAPT | |
| SCHEMBL29833357 | 0.82 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2CYP1A2CYP2D6MAPT | |
| SCHEMBL19214788 | 0.81 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2CYP1A2CYP2D6MAPT | |
| SCHEMBL12069840 | 0.80 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2CYP1A2CYP2D6MAPT | |
| SCHEMBL28030272 | 0.79 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2CYP1A2CYP2D6MAPT | |
| SCHEMBL28030840 | 0.79 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2CYP1A2CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4712965-A2 | BENZIMIDAZOLE AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | Springworks Therapeutics, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| US-20240383891-A1 | BENZIMIDAZOLE AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | CISTIM LEUVEN VZW (BE) | 2024-11-21 | — | — | US | disclosed |
| WO-2024238738-A2 | BENZIMIDAZOLE AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | SPRINGWORKS THERAPEUTICS, INC. (US) | 2024-11-21 | — | — | WO | disclosed |
| US-20100228012-A1 | PENDANT FATTY ACID IMAGING AGENTS | MOLECULAR INSIGHT PHARMACEUTICALS, INC. | 2010-09-09 | — | — | US | disclosed |
| US-7556794-B2 | Pendant fatty acid imaging agents | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2009-07-07 | — | — | US | disclosed |
| US-20070128119-A1 | Pendant fatty acid imaging agents | MOLECULAR INSIGHT PHARMACEUTICALS, INC. | 2007-06-07 | — | — | US | disclosed |
| US-7179444-B2 | Pendant fatty acid imaging agents | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2007-02-20 | — | — | US | disclosed |
| EP-1490114-A1 | PENDANT FATTY ACID IMAGING AGENTS | Biostream, Inc. (US) | 2004-12-29 | — | — | EP | disclosed |
| US-20040081616-A1 | Pendant fatty acid imaging agents | BIOSTREAM, INC. | 2004-04-29 | — | — | US | disclosed |
| WO-2003084575-A1 | PENDANT FATTY ACID IMAGING AGENTS | BIOSTREAM, INC. (US) | 2003-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240383891-A1 | BENZIMIDAZOLE AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | YAP1, TEAD2, TEAD1 | ALDH1A1 1849/4885SMN1; SMN2 2607/4885CYP1A2 3667/4885 |
| US-20070128119-A1 | Pendant fatty acid imaging agents | FABP3, CPT1B, FABP1 | ALDH1A1 986/4885SMN1; SMN2 2006/4885CYP1A2 4136/4885 |
| US-20100228012-A1 | PENDANT FATTY ACID IMAGING AGENTS | FABP3, CPT1B, FABP1 | ALDH1A1 986/4885SMN1; SMN2 2006/4885CYP1A2 4136/4885 |
| US-20040081616-A1 | Pendant fatty acid imaging agents | FABP3, CPT1B, FABP1 | ALDH1A1 986/4885SMN1; SMN2 2006/4885CYP1A2 4136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.