SCHEMBL28668951

SCHEMBL28668951

COC(F)(F)c1c[c]ccc1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27592700 0.79
SCHEMBL4608409 0.78 MAPK1 (0.37) ALDH1A1
SCHEMBL3605948 0.77 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL3608833 0.77 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL3371 0.76 TSHR (0.48) ALDH1A1TSHR
Water SCHEMBL27821326 0.76 TSHR (0.48) ALDH1A1TSHR
SCHEMBL28820080 0.76 KCNN4 (0.30)
SCHEMBL28929730 0.76
SCHEMBL11091542 0.74 CYP19A1 (0.37) ALDH1A1
Benzene SCHEMBL8005754 0.74 TSHR (0.52) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113727758-A Bicyclic heterocyclic compounds and use thereof 锐新医药公司 2021-11-30 CN disclosed