Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 6/20 | 0.70 |
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | CRHBP | P24387 | 1/20 | 0.67 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | F10 | P00742 | 3/20 | 0.61 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3259707 | 0.90 | NOD2 (0.71) | NOD2NOD1KMT2AMEN1KDM4E | |
| SCHEMBL6752352 | 0.89 | KDM4E (0.71) | NOD2NOD1KMT2AMEN1KDM4E | |
| SCHEMBL15622712 | 0.86 | KDM4E (0.68) | NOD2NOD1KMT2AMEN1KDM4E | |
| SCHEMBL18202169 | 0.86 | MEN1 (0.74) | NOD2NOD1KMT2AMEN1KDM4E | |
| SCHEMBL7425465 | 0.86 | MEN1 (0.79) | NOD2NOD1KMT2AMEN1KDM4E | |
| SCHEMBL25955240 | 0.86 | NOD2 (0.67) | NOD2NOD1KMT2AMEN1KDM4E | |
| SCHEMBL16201674 | 0.86 | MEN1 (0.74) | NOD2NOD1KMT2AMEN1KDM4E | |
| SCHEMBL13742183 | 0.85 | KDM4E (0.70) | NOD2NOD1KMT2AMEN1KDM4E | |
| SCHEMBL18322286 | 0.85 | KDM4E (0.73) | NOD2NOD1KMT2AMEN1KDM4E | |
| SCHEMBL30489155 | 0.85 | KDM4E (0.73) | NOD2NOD1KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109748840-B | Synthetic method of 2-substituted indole derivative | 中国医学科学院药物研究所 | 2021-12-07 | — | — | CN | disclosed |