Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 6/20 | 0.71 |
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.68 |
| ▸ | CRHBP | P24387 | 1/20 | 0.68 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | F10 | P00742 | 3/20 | 0.62 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28669136 | 0.90 | NOD2 (0.70) | NOD2NOD1MEN1KMT2AKDM4E | |
| SCHEMBL16201674 | 0.87 | MEN1 (0.74) | NOD2NOD1MEN1KMT2AKDM4E | |
| SCHEMBL25955240 | 0.87 | NOD2 (0.67) | NOD2NOD1MEN1KMT2AKDM4E | |
| SCHEMBL7425465 | 0.87 | MEN1 (0.79) | NOD2NOD1MEN1KMT2AKDM4E | |
| SCHEMBL6752352 | 0.87 | KDM4E (0.71) | NOD2NOD1MEN1KMT2AKDM4E | |
| SCHEMBL18202169 | 0.87 | MEN1 (0.74) | NOD2NOD1MEN1KMT2AKDM4E | |
| SCHEMBL30489155 | 0.86 | KDM4E (0.73) | NOD2NOD1MEN1KMT2AKDM4E | |
| SCHEMBL7423741 | 0.86 | KMT2A (0.73) | NOD2NOD1MEN1KMT2AKDM4E | |
| SCHEMBL13742183 | 0.86 | KDM4E (0.70) | NOD2NOD1MEN1KMT2AKDM4E | |
| SCHEMBL18322286 | 0.86 | KDM4E (0.73) | NOD2NOD1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794379-A | 1H- indole-2-carboxamide derivatives and its preparation method and application | 华东师范大学 | 2018-11-13 | — | — | CN | disclosed |
| WO-2010065310-A1 | INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE | VIA PHARMACEUTICALS, INC (US) | 2010-06-10 | — | — | WO | disclosed |
| EP-1966134-A1 | NOVEL FUSED PYRROLE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007068621-A1 | NOVEL FUSED PYRROLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-06-21 | — | — | WO | disclosed |
| WO-2006040646-A1 | BENZIMIDAZOLE OR INDOLE AMIDES AS INHIBITORS OF PIN1 | PFIZER, INC. (US) | 2006-04-20 | — | — | WO | disclosed |
| US-4260628-A | 2-Guanidinomethyl-indolines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-04-07 | — | — | US | disclosed |
| US-4137313-A | ANTICOAGULANTS, ANTIPHLOGISTIC AGENTS | BOEHRINGER INGELHEIM GMBH (DE) | 1979-01-30 | — | — | US | disclosed |